Drugs contraindicated in pregnancy, may exert their effects at any stage of pregnancy, but the greatest number of reliable information obtained by monitoring the influence of drugs during the period of organogenesis (between 18 and 55 days) in the period of development and growth of the fetus (after56 days).
Unfortunately, teratogenic effects in humans are difficult to predict, based on experimental data which were obtained in animals.For example, a sleeping pill thalidomide is present teratogen, while at the time the drug is often prescribed to pregnant women around the world.With all that in the conduct of experiments on animals no teratogenic effects were observed.
Among other things, the identification of these complications of drug treatment is difficult, and even the natural background fetal anomalies that are associated with other causes (alcoholism, ecology, viral infections, and others.).
There are many drugs that are potentially dangerous from the standpoint of teratogenesis, and the effect
As a result of the data obtained after carrying out experiments on humans and mostly animal drugs in our time are classified according to the degree of risk to the unborn child in some countries (Australia, USA).Drugs are divided into categories of A, it is safe, to D, which are dangerous to prescribe during pregnancy.
also highlighted category X - drugs is absolutely contraindicated in pregnant women.This is due to the fact that the risk of using much more than the use of the low therapeutic effect.
list of products from the category X:
- hormonal contraceptives;
- antihypertensives (chlorothiazide, reserpine);
- number of antibiotics (tetracycline, streptomycin);
- vitamin A, if the dose is greater than 10,000 IU per day;
- analgesics (indomethacin, aspirin).
Partly contraindicated following drugs:
- some vaccinations (although the damage from the use of the vaccine during pregnancy has not been proved);
- agents that cause side effects and are appointed by the doctor only when it is necessary for the health of the pregnant woman;
- insufficiently investigated drugs (risk from the use is not proven, but not refuted).
also worth bearing in mind that a woman can not be used, not only drugs during pregnancy, but also a number of herbs.For example, nettle, mother and stepmother, comfrey, magnolia, juniper, Stephanie, and others.
Before taking the drug, the pregnant woman should study carefully the summary, as there's sure to indicate whether you can use this medicine during pregnancy and the periodlactation.To be safe, you can consult with a specialist.
When prescribing and determining the dose the doctor must take into account not only the impact of a pregnancy, but also the impact of pregnancy on the effects of drugs.This is due to the fact that during pregnancy changes the absorption, distribution and excretion of drugs.In addition, the concentration changes during pregnancy proteins, extracellular fluid volume, changes in the third trimester of the kidneys and liver, and they are involved in the processing and excretion of drugs.
Reception contraindicated funds should stop even during the pregnancy planning, and both women and men.In the event of pregnancy should be careful: to follow the doctor's recommendations and beware of uncontrolled supplementation.